Sicario: Day of the Soldado (also known as Sicario 2: Soldado and Soldado) is a 2018 American action-thriller film[5] directed by Stefano Sollima and written by Taylor Sheridan. A sequel to 2015’s Sicario, the film features Benicio del Toro, Josh Brolin, Jeffrey Donovan, and Raoul Trujillo reprising their roles, with Isabela Moner, Manuel Garcia-Rulfo, and Catherine Keener joining the cast. The story relates to human trafficking at the U.S.-Mexico border and an attempt by the United States government to incite increased conflict among the cartels.

Sicario: Day of the Soldado was released in the United States and Canada on June 29, 2018, by Sony Pictures Releasing under its Columbia Pictures label, while it was distributed internationally by Lionsgate (excluding Latin America and Spain, where it was distributed by Sony).

A suicide bombing by ISIS in a Kansas City grocery store kills fifteen people. In response, the United States government orders CIA officer Matt Graver to apply extreme measures to combat Mexican drug cartels who are suspected of having smuggled the terrorists across the Mexico–United States border. Graver and the Department of Defense decide the best option is to instigate a war between the major cartels, and Graver recruits operative Alejandro Gillick for the mission. Graver also meets with PMC entrepreneur Andy Wheeldon to purchase mercenaries, helicopters, and encrypted communication equipment in order for the U.S. to maintain plausible deniability while combating the Mexican cartels.

Gillick assassinates a high-profile lawyer of the Matamoros cartel in Mexico City while Graver and his team kidnap Isabel Reyes, the daughter of Carlos Reyes (kingpin of the Sonoran cartel, rivals of the Matamoros), in a false flag operation.

Graver, Gillick and their team take Isabel to a safe house in Texas and stage a DEA raid pretending to rescue her from the Matamoros cartel. They take her to an American military base while the team organizes her return to Mexico. They plan to leave her behind in a Mexican Federal Police depot located inside territory controlled by her father’s rivals to further escalate the inter-cartel conflict. However, after they cross into Mexico, the corrupt police escort turns against them and attacks the American armored vehicles. In the firefight that ensues, Graver and his team kill 25 Mexican policemen to escape the ambush.

Amidst the chaos, Isabel runs away into the desert. Gillick goes after her alone while the rest of the team returns to the United States. Meanwhile, the American government determines that at least two of the suicide bombers in Kansas City were in fact domestic terrorists, not foreign nationals, and thus were not smuggled into the United States by the cartels. To quell tensions with Mexico, the Secretary of Defense orders the CIA to abandon the mission. Learning that Isabel witnessed the Americans shooting the Mexican police, the Secretary orders the team to erase all proof of American involvement by killing Isabel and Gillick. Graver in turn warns Gillick and orders him to kill Isabel, but Gillick refuses and turns rogue in order to keep her alive. Both have found shelter at an isolated farm in the desert for the night. Gillick knows that if they stay in Mexico, Isabel will be killed. With few resources, they disguise themselves as illegal immigrants and pay human traffickers to help them re-enter the United States. Graver and his team fly covertly into Mexico on Black Hawks, tracking a GPS device that Gillick has activated and embedded into Isabel’s shoe.

At the point of departure for the border, Miguel, a young Mexican-American who has been recruited as a coyote, recognizes Gillick from an encounter in a Texas parking lot two days earlier. He alerts his boss, who takes Gillick and Isabel hostage. As a gang initiation, Miguel is forced to shoot a hooded Gillick in the head. Upset, Miguel abandons the gang and walks off by himself. Graver witnesses the apparent killing of Gillick through live satellite imaging and his team track down and eliminate the Mexican gang. They find Isabel, and defying his own orders, Graver decides to bring her to the U.S. and place her in witness protection. Meanwhile, Gillick regains consciousness, having been shot through the cheek. He is chased by a gang search party but he kills its members by throwing a grenade into the pursuing car.